Composition

• Mupirocin USP — 2% w/w: a topical antibacterial medicine that inhibits the growth of susceptible bacteria responsible for certain skin infections.

A 2% w/w ointment contains 20 mg of mupirocin per gram of ointment. Refer to the original packaging for the complete list of ingredients.

Product Introduction

TITO Ointment is a topical antibiotic intended for selected bacterial skin infections. A healthcare professional may recommend mupirocin for conditions such as impetigo or other susceptible superficial skin infections, depending on the diagnosis and product labelling.

It does not treat viral or fungal infections and should not be used for every rash, wound or skin irritation. Unnecessary or prolonged antibiotic use can contribute to antimicrobial resistance.

Uses of TITO Ointment

• Treatment of impetigo caused by susceptible bacteria, when indicated.
• Treatment of selected bacterial skin infections as directed by a healthcare professional.
• May be prescribed for certain localised infections involving susceptible bacteria, depending on the diagnosis.

The exact approved indications may vary by product and country. Use this ointment only for the condition for which it was recommended.

Potential Benefits

• Acts locally against susceptible bacteria on the skin.
• Can help clear certain superficial bacterial skin infections when used appropriately.
• May help reduce infection-related redness, crusting or discharge as the infection improves.

Improvement depends on the type of infection, the bacteria involved and correct use. Not all skin infections respond to mupirocin.

Possible Side Effects

Possible side effects include burning, stinging, itching, redness, dryness or irritation at the application site. Some people may develop a skin sensitivity reaction.

Seek urgent medical attention for swelling of the face, lips or throat, breathing difficulty, widespread rash or faintness, as these may indicate a serious allergic reaction. Stop applying the ointment and seek medical advice if severe irritation or a new rash develops.

How to Use

• Use only as directed by your doctor or pharmacist.
• Wash your hands before and after applying the ointment.
• Gently clean and dry the affected area, then apply a thin layer as instructed.
• A suitable dressing may be used if recommended by your healthcare professional.
• Do not mix it with other creams or ointments on the same area unless advised by a healthcare professional.
• Complete the prescribed course. Do not use it for longer than recommended; seek medical advice if the infection is not improving within a few days or gets worse.

Application frequency and treatment duration should follow the product leaflet and your prescriber's instructions. Do not reuse leftover antibiotic ointment for a different problem.

How It Works

Mupirocin inhibits bacterial isoleucyl-transfer RNA synthetase, an enzyme required for protein synthesis. This interferes with the bacteria's ability to produce essential proteins and helps stop susceptible bacteria from multiplying.

Its activity is directed against certain bacteria; it is not an effective treatment for fungal infections, viral rashes or other non-bacterial skin conditions.

Safety Advice

• External use only: Do not swallow the ointment.
• Eyes and nose: Avoid contact with the eyes, inside the nose and other mucous membranes. This skin ointment is not the same as a nasal mupirocin formulation.
• Allergy: Do not use it if you are allergic to mupirocin or any ingredient in the product.
• Kidney problems: Consult your healthcare professional before using it on large areas of damaged skin or open wounds, especially if you have kidney impairment.
• Pregnancy and breastfeeding: Ask your doctor or pharmacist before use if you are pregnant, planning pregnancy or breastfeeding.
• Persistent infection: If symptoms worsen or do not improve within a few days, contact your healthcare professional for reassessment.
• Antibiotic stewardship: Do not use the ointment unnecessarily or repeatedly without medical advice.