Product Introduction

LEVOKAND-M Tablet combines two medicines that target different pathways involved in allergic symptoms. Levocetirizine blocks histamine, which contributes to sneezing, itching and a runny nose. Montelukast blocks leukotriene receptors, reducing the effects of these inflammatory substances.

This combination may be prescribed for selected patients with allergy symptoms. It is not suitable for everyone, and the need for montelukast should be assessed carefully because of its potential neuropsychiatric adverse effects.

Uses of LEVOKAND-M Tablet

• Allergic rhinitis: May help relieve sneezing, runny nose, nasal itching and associated allergy symptoms when prescribed appropriately.
• Allergy-related symptoms: The antihistamine component can help relieve itching and watery eyes associated with allergies.
• Selected patients with coexisting conditions: A clinician may consider the combination when evaluating allergy symptoms alongside other respiratory conditions.

Montelukast is not a rescue medicine for sudden asthma attacks. For allergic rhinitis, it is generally reserved for patients who do not respond adequately to or cannot tolerate alternative treatments, following an assessment of risks and benefits.

Benefits / Potential Benefits

• Levocetirizine may reduce sneezing, nasal itching, runny nose and watery eyes caused by allergies.
• Montelukast blocks leukotriene activity involved in allergic inflammation.
• The two ingredients work through different mechanisms and may provide symptom relief for selected patients.
• When appropriately prescribed, treatment may help improve comfort and daily functioning affected by allergy symptoms.

Results vary by individual and condition. The combination does not cure allergies, and its benefits must be weighed against the potential risks of montelukast.

Possible Side Effects

Possible side effects associated with these ingredients include:

• Sleepiness, fatigue or dizziness.
• Headache or dry mouth.
• Nausea or abdominal discomfort.
• Sleep disturbances or unusual dreams.
• Changes in mood or behaviour, anxiety, irritability or depression.
• Rarely, suicidal thoughts or behaviour and other serious neuropsychiatric reactions have been reported with montelukast.

How to Use LEVOKAND-M Tablet

• Use this medicine only as directed by your doctor or pharmacist.
• Follow the prescribed schedule and the instructions on the product label.
• Swallow the tablet with water according to the product instructions.
• Levocetirizine can cause drowsiness. Avoid driving or operating machinery if you feel sleepy or dizzy.
• Do not take extra tablets or combine it with other allergy medicines unless advised by a healthcare professional.
• Do not use this tablet to treat a sudden asthma attack or severe breathing difficulty.

The correct dose and duration depend on the patient's age, diagnosis, kidney function and prescribing instructions. Do not assume this strength is suitable for children or every patient.

How It Works

Levocetirizine: Blocks histamine H1 receptors. Histamine contributes to itching, sneezing, watery eyes and a runny nose during an allergic response.

Montelukast: Blocks cysteinyl leukotriene receptors, reducing the effects of leukotrienes involved in airway inflammation and allergy-related symptoms.

By targeting different pathways, the ingredients may provide complementary symptom relief in selected patients. Montelukast does not replace prescribed inhalers or emergency treatment for acute asthma symptoms.

Safety Advice

• Mood and behaviour: Monitor for agitation, aggression, anxiety, depression, sleep changes, unusual dreams or suicidal thoughts. Contact a healthcare professional immediately if these occur.
• Drowsiness: Levocetirizine may cause sleepiness. Avoid alcohol and use caution with sedatives or other medicines that cause drowsiness.
• Kidney disease: Tell your doctor if you have reduced kidney function. Levocetirizine dosing may require adjustment, and severe kidney impairment may make it unsuitable.
• Asthma: Continue prescribed controller and rescue medicines as directed. This combination is not a replacement for a rescue inhaler.
• Pregnancy and breastfeeding: Ask your doctor or pharmacist to assess whether this combination is appropriate for you.
• Other medicines: Tell your healthcare professional about all medicines and supplements, especially sedatives or other antihistamines.
• Children: Do not give this 5 mg/10 mg tablet to a child unless a qualified clinician confirms the formulation and dose are appropriate.
• Allergic rhinitis: Discuss alternative treatments if symptoms are mild or can be managed with other suitable medicines, because montelukast has a serious neuropsychiatric warning.

Quick Tips

• Use the combination only when prescribed for your symptoms and circumstances.
• Read the patient information leaflet and understand the warning about mood and behaviour changes.
• Seek professional advice if allergy symptoms persist despite treatment.
• Avoid alcohol or sedating medicines if they worsen drowsiness.
• Do not use this medicine as emergency treatment for severe breathing difficulty.
• Store the tablets according to the packaging instructions and keep them out of children's reach.
• Check the expiry date and do not use tablets from damaged packaging.