1. Product Introduction

CLAVKAND-DS combines amoxycillin with clavulanic acid. Amoxycillin interferes with bacterial cell-wall formation, while clavulanic acid inhibits certain beta-lactamase enzymes that can otherwise break down amoxycillin.

This combination may be useful against selected susceptible bacteria, including some bacteria that produce beta-lactamase enzymes. The appropriate medicine depends on the diagnosis, suspected organism and patient's clinical circumstances.

2. Uses of Medicine

When prescribed for an appropriate susceptible bacterial infection, amoxycillin and clavulanic acid may be used for selected conditions, including:

• Some ear and sinus infections.
• Selected respiratory tract infections.
• Skin and soft-tissue infections.
• Dental infections.
• Other susceptible bacterial infections for which this combination is appropriate.

Not every infection requires this antibiotic. It should not be used to treat viral infections or taken without a valid prescription.

3. Potential Benefits

• Combines an antibiotic with an inhibitor of certain bacterial resistance enzymes.
• Can treat some susceptible bacterial infections when selected appropriately.
• Provides an oral suspension option for patients who need a liquid formulation.
• May support recovery when the medicine, dose and duration are appropriate for the infection.

Benefits vary according to the organism, infection site, severity, correct administration and the patient's individual health factors.

4. Possible Side Effects

Possible side effects include:

• Diarrhoea or loose stools.
• Nausea or vomiting.
• Abdominal discomfort.
• Skin rash, itching or allergic reactions.
• Fungal overgrowth, such as oral thrush.
• Rarely, liver problems, including hepatitis or jaundice.

Seek urgent medical attention for breathing difficulty, swelling of the face or throat, a severe blistering rash, yellowing of the eyes or skin, or severe or persistent diarrhoea, particularly if bloody.

5. How to Use

• Use only when prescribed by a qualified healthcare professional.
• Follow the manufacturer's instructions for preparing the dry syrup. Do not guess the amount of water required.
• Shake the prepared suspension as directed before measuring each dose.
• Use an appropriate oral measuring syringe or measuring device rather than a household spoon.
• Follow the prescribed dose, intervals and treatment duration.
• Follow the package instructions for storage and the period during which the prepared suspension can be used.

The correct amount for a child depends on factors such as body weight, infection, age and kidney function. No individual dose is provided on this page.

6. How It Works

Amoxycillin interferes with bacterial cell-wall synthesis, which can lead to the death of susceptible bacteria.

Clavulanic acid blocks certain beta-lactamase enzymes that can inactivate amoxycillin. This helps preserve the antibiotic's activity against some bacteria, but it does not overcome every form of antibiotic resistance.

7. Safety Advice

• Penicillin allergy: Inform the prescriber about any previous serious reaction to amoxycillin, penicillins, clavulanic acid or related antibiotics.
• Liver history: Tell the clinician if you previously developed jaundice or liver problems while taking this combination.
• Kidney disease: The dose or treatment choice may need adjustment.
• Other medicines: Report all medicines, especially anticoagulants, methotrexate, probenecid or allopurinol.
• Young children: Use the exact prescribed dose and measuring device. Do not estimate a dose from age alone.
• Pregnancy or breastfeeding: Ask a healthcare professional whether the medicine is appropriate.
• Persistent diarrhoea: Seek medical advice, including if it develops after the antibiotic course.

8. Quick Tips

• Check the product label for the exact strength per measured volume.
• Use the supplied preparation and storage instructions.
• Measure each dose accurately with an oral syringe or suitable measuring device.
• Do not share the medicine or use leftover antibiotics for another illness.
• Follow the prescribed treatment plan and do not change the dose yourself.
• Keep the medicine out of children's reach.
• Contact the prescriber if symptoms worsen or fail to improve as expected.